N1o1 by Pneuma Nitric Oxide
We are based on groundbreaking research into replenishing the Nitric Oxide that’s lost as we age.
Unlocking the transformative power of Nitric Oxide, our groundbreaking solutions redefine the nexus of health and beauty. Dive into a world where comprehensive skin revitalization meets the zenith of cognitive and physical well-being. Experience skin that radiates youth, a heart that beats with vitality, and a mind that thrives with clarity. Elevate your life with optimal heart health and circulation, ensuring every cell is nourished and every moment is lived to the fullest.
Your blood pressure isn’t the diagnosis. It’s a symptom.
By the time blood pressure rises, the underlying problem may have been developing for years.
According to Nathan Bryan, one of the earliest signs of declining vascular health is endothelial dysfunction, when the cells lining your blood vessels can no longer efficiently produce nitric oxide.
Instead of only asking “What are my numbers?” ask a better question:
“How healthy is my endothelium?”
An endothelial function test can provide insight into how well your blood vessels are functioning and may help identify issues before more serious problems develop.
Don’t settle for masking symptoms.
Ask questions. Understand the root cause. Take ownership of your health.
Knowledge is the first step toward better health.
PSA: “Your health doesn’t improve because you try harder. It improves because you’re consistent.” — Susan Shaffer Susan Shaffer, President and Co-Founder of .
One of the simplest habits you can build is supporting your body’s nitric oxide every day. No complicated routine. No major lifestyle overhaul. Just one lozenge that dissolves in your mouth and fits effortlessly into your morning or evening.
For best results, take one lozenge twice daily, approximately 12 hours apart to help support 24-hour nitric oxide coverage as part of your daily routine.
Small daily habits create long-term results. The key isn’t doing it once, it’s making it part of your lifestyle.
Support your body. Stay consistent. Let the benefits compound over time.
Big news: CardioSmile has a new name and a whole new look.
Introducing Breath of Life, a complete rebrand and package redesign by THE CHAMBERS GROUP.
Same fluoride-free, hydroxyapatite, nitric oxide, microbiome-friendly toothpaste you trust and now with an identity that matches what it does.
Because nitric oxide is the breath of life. This formula:
✔️ Restores oral nitric oxide production
✔️ Enhances microbiome diversity
✔️ Remineralizes teeth
✔️ Leaves breath fresh and minty
✔️ Supports oral health and systemic health
New name. New design. Same powerful science. Welcome to Breath of Life.
Forget stimulant-laden energy drinks and unpleasant beet taste. Experience pure nitric oxide power for clean energy!
Our N.O. Beetz fermented beet powder is pre-convereted for nitric oxide production, delivering all the benefits without oxalates or beet color and taste. Mix one sachet with 2-3oz of water, take it as a shot, and feel the difference when you perform. Improve cellular hydration and mitochondrial ATP (your body’s natural energy currency).💥
Performance is earned. Science helps you get there.
When you’re a USA Track & Field National Champion competing at the highest level, every second matters.
Jerry Snider Jerry Snider stopped by the N1o1 booth during Dave Asprey Dave Asprey’s BEYOND Biohacking Conference looking for something that could support both performance and long-term health.
Before his afternoon training run in the Texas heat, he took N.O. Beetz and an N1o1 Nitric Oxide Lozenge.
The result?
“I was 10–12 seconds per mile faster than both what I was expecting and what I normally run at that time of day.”
Individual results will vary, but stories like Jerry’s are why we’re passionate about nitric oxide science.
Developed by Nathan Bryan, N1o1 products are formulated to support your body’s natural nitric oxide pathways, helping support oxygen delivery, circulation, exercise performance, recovery, and healthy aging.*
Good science doesn’t replace hard work.
It helps your body perform at its best.
We’re cheering you on, Jerry. Good luck defending your national title this July! 🏃🏆
*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
Before you can feel a difference, your body is already responding
One of the most common questions Nathan Bryan hears is: ”Will I feel anything when I take N1o1 Nitric Oxide Lozenges?”
The answer? Everyone is different, so not necessarily.
Nitric oxide is a signaling molecule that your body naturally produces. N1o1 Lozenges are designed to release nitric oxide gas as they dissolve, providing immediate nitric oxide while supporting your body’s natural physiology. Even if you don’t notice a sensation, that doesn’t mean nothing is happening.
With more than 30 years of nitric oxide research behind every formula, N1o1 is built on science, not hype.
Whether your goal is to maintain your health, stay active, or support healthy aging, the greatest benefits come from consistent daily use. Like exercise and good nutrition, nitric oxide support works best as part of your everyday routine.
Your body is working for you every second of every day. Support it with science. Support it with N1o1.
Unlocking human potential starts with the right community.
world New York brought together leading experts, breakthrough technologies, and passionate individuals united by one mission: advancing the future of health, longevity, and performance.
A defining moment was ’s keynote, sharing the groundbreaking science of nitric oxide and practical ways to support circulation, performance, healthy aging, skincare, oral health, and everyday wellness.
Beyond the stage, our favorite part was connecting with all of you, sharing the science behind , demonstrating our supplements, skincare, and oral care, and hearing your inspiring health journeys.
This is why we do what we do.
Thank you for your trust, curiosity, and commitment to living healthier every day. We’re honored to be part of your journey and grateful to continue building this movement together. 🫶
.biohackingmama .co
President and Co-Founder of , Susan Shaffer here — the Queen of Nitric Oxide and your NO bestie. 👑
If there’s one longevity hack I never skip, it’s this: Stack the hack.
Before hyperbaric oxygen, infrared sauna, IV therapy, exercise, nutritional supplements, or any wellness protocol, I start with nitric oxide.
Why?
Because nitric oxide is foundational. It helps support the body’s natural ability to deliver oxygen and nutrients where they’re needed most. When nitric oxide levels are optimized, everything else you do has the potential to work better.
That’s why it’s the first thing I reach for every day.
Don’t settle for average when you can optimize.
Start with nitric oxide. Then stack everything else on top.
Here’s to your best health. Your best performance. Your best life. Age-defy at every stage of life.
Dave Asprey’s BEYOND Biohacking Conference with Dave Asprey
When someone who understands supplements says, “This actually works.” 💪✨
Mike McNeil has spent years helping others optimize their health. He’s seen the products that overpromise and underdeliver.
After dealing with blood pressure challenges, recovery from surgery, and the daily pursuit of feeling his best, he turned to nitric oxide lozenges developed by Nathan Bryan, the world’s leading nitric oxide expert.
The result?
✔️ Better sleep
✔️ Improved mental clarity
✔️ More energy and vitality
✔️ A simple daily routine he can actually stick with
Nitric oxide is one of the most important molecules your body produces for circulation, oxygen delivery, and overall wellness. Yet production declines naturally with age.
That’s why thousands are making N1o1 part of their daily health routine.
Two lozenges a day. Backed by science. Trusted by people who know the difference.
Have you experienced the N1o1 difference yet?
*Individual experiences may vary. N1o1 products are designed to support healthy nitric oxide production and overall wellness and are not intended to diagnose, treat, cure, or prevent any disease.*
06/18/2026
Nitric oxide skincare in action.
At the recent The Stem Cell Conference, Nathan Bryan demonstrated applying the N1o1 Nitric Oxide Activating Age-Defying Serum to one hand and compared it to the untreated hand. Within minutes, many attendees noticed increased radiance and a slight pink flush on the treated side.
Why? Nitric oxide supports healthy microcirculation, helping improve the delivery of oxygen and nutrients to the skin.
Benefits of the N1o1 Nitric Oxide Activating Serum:
✨ Supports healthy circulation and skin vitality
✨ Promotes a more radiant, youthful-looking complexion
✨ Helps improve the appearance of skin tone and texture
✨ Advanced nitric oxide technology designed to support healthy aging
It’s important to remember that everybody’s skin and body are different. The temporary pink flush may vary based on individual skin tone, circulation, and nitric oxide responsiveness. Some people notice a visible flush, while others may not experience a noticeable color change.
Science. Circulation. Clinically Proven Results.
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