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Intrusion :
Tizaro is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Limitations of use:

Pharmacology

Tirzepatide is a GIP receptor and GLP-1 receptor agonist. It is a 39-amino-acid modified peptide with a C20 fatty diacid moiety that enables albumin binding and prolongs the half-life. It selectively binds to and activates both the GIP and GLP-1 receptors, the targets for native GIP and GLP-1. It enhances first and second-phase insulin secretion and reduces glucagon levels, both in a glucose dependent manner.
Contraindications

Tirzepatide is contraindicated in patients with known hypersensitivity to tirzepatide or any other components of this product. It is also contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or in patients with multiple endocrine neoplasia syndrome type 2 (MEN 2).

Side Effects

The most common side effects are nausea, diarrhea, decreased appetite, vomiting, constipation, dyspepsia and abdominal pain.







It has not been studied in patients with a history of pancreatitis.

It is not indicated for use in patients with type 1 diabetes mellitus.

venex-100mg /ventoxen-100mg(venetoclax ) is manufactured by drug international limited in bangladesh. And ventoxen fanufactured by everest pharma
they are word wide famous for supplying for medicine. general Venclexta is a traditional drug used to treat grown-ups with habitual Lymphocytic Leukemia( CLL), Small Lymphocytic Carcinoma( SLL), Acute Myeloid Leukemia( AML),, Venetoclax is a medicine that works by helping to decelerate or stop the growth of cancer cells.
side effect of( venetoclax) Diarrhea, nausea, puking, frazzle or headache may occur after eating venetoclax. but it is nothing to fear.
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Olanib is used for the returning treatment of some types of ovarian cancer in patients who have had platinum chemotherapy or a change in a gene called BRCA. Olanib is a potent oral poly(ADP-ribose) polymerase (PARP) inhibitor. Cancer cells rely on PARP to stay alive, including cancer cells whose BRCA gene changes, thus Olanib works to stop PARP from repairing DNA damage which results in the death of cancer cells.

Brand Name: Olanib
Generic Name: Olaparib
Packing 112
Form Capsule
Strength 50mg & 150mg
Manufacturer Everest Pharmaceuticals Ltd.
Country Bangladesh

Nexataf (Tenofovir Alafenamide), generic Vemlidy is a prescription medicine used to treat chronic hepatitis B (HBV) infection and liver cancer.
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(asciminib) is commonly used for treating certain kinds of Philadelphia chromosome-positive chronic myeloid leukemia (PH+ CML) in adults. Chronic myeloid leukemia (CML) is a type of blood cancer. The Philadelphia chromosome occurs when pieces of 2 chromosomes, chromosomes 9 and 22, break off and swap places. The new abnormal chromosome that is Uses
What is Scemblix used for?
Scemblix (asciminib) is commonly used for treating certain kinds of Philadelphia chromosome-positive chronic myeloid leukemia (PH+ CML) in adults. Chronic myeloid leukemia (CML) is a type of blood cancer. The Philadelphia chromosome occurs when pieces of 2 chromosomes, chromosomes 9 and 22, break off and swap places. The new abnormal chromosome that is created is known as Philadelphia chromosome-positive (PH+). The PH+ affects your bone marrow and changes your white blood cells, causing leukemia. Scemblix may be used to treat certain PH+ CML.

Scemblix may also be used for other conditions as determined by your healthcare provider.

How does Scemblix work (mechanism of action)?
Scemblix is a type of medicine known as a tyrosine kinase inhibitor (TKI). When the Philadelphia chromosome is created, it creates a fusion between two genes, known as the BCR-ABL1 fusion. Scemblix works by blocking the ABL1 part of the fusion and helps to prevent or limit changes in the bone marrow that lead to abnormal white blood cells.

How should I store Scemblix?

Scemblix should be stored at room temperature, between 68 F to 77 F (20 C to 25 C). It can be exposed to temperatures between 59 F to 86 F (15 C to 30 C) for shorter periods of time, such as when transporting it. Keep Scemblix in its original container to protect it from moisture and store in a cool, dry place.

Side Effects:

What are the most common side effects of Scemblix?
The most common side effects of Scemblix are listed below. Tell your healthcare provider if you have any of these side effects that bother you.
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Abeclib-150mg( abemaciclib) It’s Bangladeshi version, its generic name is abemaciclib, generic verzenio is a prescription medicine used to treat breast cancer known as HR+/ HER2 -(hormone receptor positive m human epidermal growth factor receptor 2 negative) breast cancer, abemaciclib It helps slow down or stop cancer cells,its manufacture by skf pharma limited in Bangladesh,

Niratinib is an oral, irreversible tyrosine kinase inhibitor. It is the only product in the world approved for intensive adjuvant therapy after treatment with HER2-positive breast cancer with trastuzumab (Herceptin) to reduce the risk of recurrence. The applicable population is to complete the standard trastuzumab adjuvant treatment of patients with undeveloped disease but high risk factors.

Indications Neratinib:
Breast cancer for women patients completed standard trastuzumab (Herceptin, Herceptin) adjuvant therapy, disease progression, but high-risk factors

Pharmacology Neratinib:
Neratinib is a kinase inhibitor that irreversibly binds to Epidermal Growth Factor Receptor (EGFR), Human Epidermal Growth Factor Receptor 2 (HER2), and HER4. Hernix reduces EGFR and HER2 autophosphorylation, downstream MAPK, and AKT signaling pathways. Therefore show antitumor activity in EGFR and/or HER2 expressing carcinoma cell lines. Neratinib human metabolites M3, M6, M7, and M11 inhibited the activity of EGFR, HER2, and HER4 in vitro. In vivo, oral administration of Hernix inhibited tumor growth in mouse xenograft models with tumor cell lines expressing HER2 and EGFR.

Baricinix-4mg

Baricinix 4mg (Baricitinib)

Product Name: Baricinix
Generic Name : Baricitinib
Formulation: Tablet
Available Pack Size: 30’s Pot
Available Strengths: 2mg & 4mg
Categories: Anti-viral, Biotech Products, Drugs to treat Hepatitis
Manufacturer: Beacon Pharmaceuticals Ltd.

Product description:

baricinix is the most popular in bangladesh. its manufactured by beacon pharmaceuticals limited.

is indicated for the treatment of moderate to severely active rheumatoid arthritis in adult patients who have responded inadequately to, or who are intolerant to one or more disease-modifying anti-rheumatic drugs. Baricitinib may be used as monotherapy or in combination with Methotrexate.
Baricinix is the first once-daily oral selective JAK1 and JAK2 inhibitor for the treatment of moderate to severe active rheumatoid arthritis (RA) who have not responded well enough to or could not tolerate at least one medicine called a tumor necrosis factor (TNF) antagonist.

Acaluxen (Acalabrutinib), generic Calquence is a prescription medicine used to treat Mantle cell lymphoma (MCL) who have received at least one treatment for their cancer, or Chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL).

(Caboxen) can help slow down cancer progression, reduce tumor size, and manage cancer-related symptoms. Learn about the benefits, usage, and safety tips for this medication. Contact your healthcare provider today to see if Cabozantinib is right for you.
What is Cabozantinib and How It Works: Cabozantinib is a medication used to treat different types of cancer, including renal cell carcinoma, hepatocellular carcinoma, and medullary thyroid cancer. It works by blocking the action of specific proteins that contribute to the growth and spread of cancer cells. Cabozantinib can help slow down or stop the progression of cancer, relieve symptoms, and improve the patient’s quality of life.
Benefits of Cabozantinib (Caboxen): Cabozantinib 20 mg is a convenient and effective treatment option for cancer patients. It can reduce the size of tumors, prevent the growth of new tumors, and help manage cancer-related symptoms such as pain, fatigue, and weight loss. Cabozantinib can also improve the patient’s overall health and well-being, allowing them to continue their daily activities and enjoy their life.
How to Take Cabozantinib (Caboxen) Safely and Effectively: Cabozantinib 20 mg should be taken as directed by the healthcare provider. It is usually taken once a day, with or without food. It is important to follow the dosing schedule and not miss any doses. Cabozantinib can cause side effects such as diarrhea, nausea, fatigue, and high blood pressure, so it is essential to inform the healthcare provider of any side effects and seek medical attention if necessary. Cabozantinib can interact with other medications, so it is crucial to inform the healthcare provider of all medications and supplements being taken.
Pregnancy
Based on findings of home enamel Mudie’s and its mechanism of action, cabozantinib can cause fetal harm when administered to a pregnant woman. There are no available data on pregnant wome

Barigen (Baricitinib), generic Olumiant is a prescription medicine used to treat rheumatoid arthritis (it is an autoimmune condition in which the body attacks its own joints and internal organs). Baricitinib decreases pain, tenderness, swelling and stiffness in the joints. Barigen manufactured by General Pharma Ltd. in Bangladesh. Barigen 4 mg (Baricitinib) is a groundbreaking medication that offers a comprehensive solution for individuals experiencing hair fall, baldness, and rheumatoid arthritis. It harnesses the power of Baricitinib, a potent Janus kinase (JAK) inhibitor, to promote hair regrowth, provide relief from rheumatoid arthritis symptoms, and improve overall quality of life. Barigen 4 mg is also proven to reduce inflammation and boost the immune system, providing additional health benefits. It is an effective and affordable treatment that can be used to manage a variety of conditions.

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