Reyoung Beaute

莱乃康胎盘素具有修复激活，再生人体已经衰老或受损的细胞，增加细胞活性的作用，从而由内到外的改善人体机能和皮肤的问题。达到回复青春，延缓衰老的作用

Laennec placental extract has the function of repairing and activating cells, regenerating aged or damaged cells, and increasing cell activity. This improves bodily functions and skin issues from the inside out, achieving the effect of restoring youthfulness and delaying aging

胎盘素在日本称为“美容原液中的女王成分”，它含有氨基酸、蛋白质、维生素、活性肽氨酸（细胞重生和增殖所必须的营养素）等丰富的营养成分，可以让皮肤在短时间内恢复最佳状态，真得有“返老还童”的神奇力量。

一般而言，胎盘素由于取自正在高速生长的组织，所以产品含有很多促进细胞活化的因子，再加上大量的小分子营养物质，对于疾病、老化和美容等都具有很好的效果。

现今胎盘素已成为人类养生学中最安全有效的滋养品，为人类带来防止衰老，重振精力的奥妙效果。

Placenta extract is known as the "queen ingredient in beauty essences" in Japan. It contains abundant nutrients such as amino acids, proteins, vitamins, and active peptides (essential nutrients for cell regeneration and proliferation), which can quickly restore the skin to its optimal condition. It is believed to have miraculous powers of "rejuvenation."

Generally, placenta extract is derived from rapidly growing tissues, thus products contain factors that promote cellular activation, along with a wealth of small molecule nutrients. It is considered highly effective for conditions such as diseases, aging, and beauty treatments.

Today, placenta extract has become one of the safest and most effective nourishing agents in human health studies, bringing miraculous effects in anti-aging and revitalization.

清宫太医私传，慈禧太后在中年以后就长年服食足月头胎胎盘，以养容颜。
在美国女画家卡尔为慈禧所画的肖像中，慈禧虽时年过半百，却面容娇媚，风韵迷人，俨然一位中年贵妇，其养生美容之道中，胎盘的作用可见之一

不止中国，在西方，宫廷也有服用胎盘的历史，十八世纪法国路易十六的王妃以及传说中的美女玛莉爱德华，都服用过胎盘

According to private records of imperial physicians, Empress Dowager Cixi of the Qing Dynasty consumed full-term placentas for many years in her later life to maintain her youthful appearance. In the portrait of Empress Dowager Cixi painted by American artist Katharine Carl, despite being over fifty years old, Cixi appears charming and graceful, resembling a middle-aged noblewoman. This suggests that the placenta played a significant role in her beauty regimen.

The practice of consuming placenta was not limited to China. In the West, there is historical evidence of its use in royal courts as well. In the 18th century, Queen Marie Antoinette of France and the legendary beauty Mary Edward were both reported to have consumed placenta.

据史料记载，中国历史上紫河车最早将胎盘作为保健养生用物的当首推在2200年前统一中国的秦始皇，公元前219年，40岁的秦始皇沿渤海湾东行，巡视京都海疆，寻找长生不老之药。找遍天下长生不老的处方，竟是胎盘。秦始皇便将其推崇为长生不老药。自此之后，胎盘一直做为皇室养生之上品。

According to historical records, the earliest recorded use of placenta for health and longevity purposes in Chinese history dates back to Emperor Qin Shi Huang, who unified China around 2200 years ago. In 219 BCE, at the age of 40, Emperor Qin Shi Huang traveled east along the Bohai Bay to inspect the borders of his kingdom in search of the elixir of immortality. After searching far and wide for such a remedy, it was found that placenta held the key. Emperor Qin Shi Huang then esteemed it as the elixir of immortality. Since then, placenta has been revered as a supreme health tonic within the imperial court.

一个千年的梦想：不惧衰老之胎盘素

胎盘在中国中医界还是很有名的，名叫紫河车，即人出生时所脱掉的胎盘，经过加工干燥而成，这是一味十分著名的中药药材，始载于“本草拾遗”，在李时珍的《本草纲目》中，也有所记载。
中医曾视“胎盘”为滋补上品，认为它能医治和调节人体各器官的生理功能，激活人体内的衰老细胞及细胞再生功能，使身体各部位生理功能恢复到几年、甚至几十年前的状态，使人精力旺盛，青春焕发。功效听起来如此神奇，来源又十分与众不同

A Millennium Dream: Fearless Aging with Placenta Extract

In traditional Chinese medicine, the placenta is quite renowned and is known as "Zi He Che," which refers to the placenta discarded at birth, processed, and dried. It is a famous medicinal herb first recorded in "Supplement to Materia Medica" and also mentioned in Li Shizhen's "Compendium of Materia Medica."

Traditional Chinese medicine has long regarded the placenta as a top-grade tonic, believing it can heal and regulate the physiological functions of various organs, activate aging cells, and promote cell regeneration. This, in turn, is thought to restore the physiological functions of various body parts to the state they were in years or even decades ago, making individuals full of energy and youthful vigor. The effects sound incredibly miraculous, and the origin is indeed quite unique.

早在公元前世界各地就开始利用胎盘来治疗各种疾病，以及保持健康和青春。现在的生物技术日益进步，胎盘的利用是“再生医学”前沿领域的一部分。

株式会社日本生物制剂是该领域中领先全球的公司。 JBP一直潜心研究胎盘类产品，以及致力于解开胎盘素带给人类更大福音的密码。我们的宗旨是让胎盘的各种功能在医药、化妆品和保健品领域中更加有效地应用。

Since ancient times, cultures worldwide have utilized the placenta for treating various ailments and maintaining health and youthfulness. With the advancement of biotechnology, placental utilization has become a frontier in regenerative medicine.

Japan Bio Products Co., Ltd. is a global leader in this field. JBP has been dedicated to researching placental products and unlocking the secrets of placental extracts for the benefit of humanity. Our mission is to harness the diverse functionalities of the placenta more effectively in the fields of pharmaceuticals, cosmetics, and health supplements.

株式会社日本生物制剂(Japan Bio Products Co., Ltd.) JBP从1956年开始致力于胎盘素研究，是全球较早开始胎盘素研究的机构，现在则是世界上最先进的胎盘素药物以及化妆品、保健品制造企业。

胎盘位于母亲的子宫内保护胚胎发育成胎儿，是只有哺乳动物才拥有的一种临时器官。胎盘内含有控制基因信息的信号，管理各种新细胞的诞生。出于这个原因，胎盘被称为生命的 “信息库”。

“胎盘” = “赐予生命的祝福 ”

Japan Bio Products Co., Ltd. (JBP) has been dedicated to placental research since 1956, making it one of the earliest institutions globally to delve into this field. Today, it stands as the foremost manufacturer of placental-based pharmaceuticals, cosmetics, and health supplements worldwide.

The placenta, situated within the mother's uterus, shields the developing embryo, nurturing it into a fetus. It is a temporary organ unique to mammals, containing signaling molecules that regulate the generation of various new cells. Due to this characteristic, the placenta is often referred to as the "information bank" of life.

"Placenta" = "Blessing of Life"

肝细胞生长因子（HGF）

HGF是一种干细胞来源的生长因子，其结构实质是含728个氨基酸的肝素结合糖蛋白，它来自间质细胞，存在于动物和人体内多种组织和细胞中，以旁分泌方式作用于邻近细胞，与细胞表面的受体结合并激活酪氨酸激酶活性，从而发挥其较强的促有丝分裂、诱导血管生成等生物学作用。

Hepatocyte Growth Factor (HGF)

HGF is a growth factor derived from stem cells, with a structure consisting of 728 amino acids forming a heparin-binding glycoprotein. It originates from stromal cells and is present in various tissues and cells in both animals and humans. It acts on adjacent cells in a paracrine manner, binding to receptors on the cell surface and activating tyrosine kinase activity, thereby exerting its potent biological effects such as promoting mitosis and inducing angiogenesis.

神经生长因子（NGF）

NGF是最早发现和最典型的神经营养因子，同时也是影响神经系统最重要的生物活性分子之一，其包含α、β、γ三个亚基组成，其中β亚基（β-NGF）是唯一具有生物学活性的亚基。β亚单位通过非共价键结合而构成活性二聚体，其中，六个半胱氨酸残基之间由二硫键相连，若二硫键结构不正确，NGF将丧失其生物活性。NGF的表达水平通常在慢性神经系统疾病中增加，NGF与其受体TrkA结合激活TrkA细胞内结构域激酶和下游信号通路的磷酸化，导致神经递质的产生和异位放电，从而致使了疼痛的产生。

Nerve Growth Factor (NGF)

NGF is the earliest discovered and most typical neurotrophic factor, and it is also one of the most important bioactive molecules affecting the nervous system. It consists of three subunits: α, β, and γ, among which the β subunit (β-NGF) is the only one with biological activity. The β subunit forms an active dimer through non-covalent bonds, with six cysteine residues connected by disulfide bonds. If the disulfide bond structure is incorrect, NGF will lose its biological activity. The expression level of NGF is usually increased in chronic nervous system diseases. NGF binds to its receptor TrkA, activating the intracellular kinase domain of TrkA and downstream signaling pathways, leading to the production of neurotransmitters and ectopic discharge, thus causing pain.

类胰岛素生长因子（IGF）

IGF是一种受生长激素（GH）调节的单链多肽，由70个氨基酸组成，分子量为7649 Da，结构有45%与胰岛素相似。可由肝、肾、肺、心、脑和肠等组织产生，其中大部分在肝脏合成，再释放入血液中作用于靶细胞，以达到促进生长、调节代谢的作用。IGF有IGF-1和IGF-2两种，IGF-2，主要对胎儿的生长起作用，而IGF-1是AKT信号转导途径中的一种有效天然激活剂、细胞生长和增殖的刺激因子、细胞程序性死亡的有效抑制因子。

Insulin-like Growth Factor (IGF)

IGF is a single-chain peptide regulated by growth hormone (GH), consisting of 70 amino acids with a molecular weight of 7649 Da. Its structure bears a 45% similarity to insulin. It can be produced by various tissues including the liver, kidneys, lungs, heart, brain, and intestines, with the liver being the primary site of synthesis. IGF is then released into the bloodstream to act on target cells, promoting growth and regulating metabolism. There are two types of IGF: IGF-1 and IGF-2. IGF-2 primarily plays a role in fetal growth, while IGF-1 serves as a potent natural activator of the AKT signaling pathway, a stimulatory factor for cell growth and proliferation, and an effective inhibitor of programmed cell death.

成纤维细胞生长因子（FGF）

FGF是一类由垂体和下丘脑分泌的多肽生长因子，以肝素/硫酸肝素作为辅助因子与其受体结合从而发挥作用，FGF对成纤维细胞有促分裂作用，可通过参与调节细胞增殖、迁移、分化和凋亡在胚胎的发育和维持机体稳定中发挥重要作用。FGF有酸性（αFGF）和碱性（βFGF）两种。其中αFGF仅分布于神经组织，βFGF普遍存在于多种组织，如脑垂体、视网膜、肾上腺、胎盘、前列腺、免疫组织系统和各种肿瘤细胞中，以垂体中含量最大。

Fibroblast Growth Factor (FGF)

FGF is a type of peptide growth factor secreted by the pituitary gland and hypothalamus. It exerts its effects by binding to its receptors with heparin/sulfated heparin as a co-factor. FGF has a mitogenic effect on fibroblast cells and plays an important role in embryonic development and maintaining organism stability by regulating cell proliferation, migration, differentiation, and apoptosis. FGF exists in two forms: acidic (αFGF) and basic (βFGF). αFGF is exclusively distributed in neural tissues, while βFGF is widely present in various tissues such as the pituitary gland, retina, adrenal glands, placenta, prostate, immune system, and various tumor cells, with the highest content in the pituitary gland.

转化生长因子（TGF）

TGF是一种细胞质内由氨基酸组成的蛋白质，包括两类多肽类生长因子，转化生长因子-α（TGF-α）和转化生长因子-β（TGF-β）。TGF-α是由巨噬细胞，脑细胞和表皮细胞产生，可诱导上皮发育。TGF-β是一种多功能蛋白质，由成骨细胞和软骨细胞合成，通过与细胞膜表面特异性受体结合发挥生物学作用，调节成骨细胞增殖、分化。TGF-β对破骨细胞具有促进和抑制的双向作用，与骨细胞外基质代谢有关，并能够促进软骨细胞的生成

Transforming Growth Factor (TGF)

TGF is a cytoplasmic protein composed of amino acids, including two classes of peptide growth factors, Transforming Growth Factor-α (TGF-α) and Transforming Growth Factor-β (TGF-β). TGF-α is produced by macrophages, brain cells, and epithelial cells and can induce epithelial development. TGF-β is a multifunctional protein synthesized by osteoblasts and chondrocytes, which exerts its biological effects by binding to specific receptors on the cell membrane, regulating osteoblast proliferation and differentiation. TGF-β has a dual effect on osteoclasts, promoting and inhibiting, and is involved in bone cell extracellular matrix metabolism, and can promote chondrocyte generation.