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𝗚𝗹𝘂𝘁*𝘁𝗵!𝗼𝗻ę 𝗧𝗔𝗗 𝟲𝟬𝟬 𝘩𝘦𝘭𝘱𝘴 𝘥𝘦𝘵𝘰𝘹 𝘵𝘩𝘦 𝘭𝘪𝘷𝘦𝘳, 𝘴𝘵𝘳𝘦𝘯𝘨𝘵𝘩𝘦𝘯 𝘪𝘮𝘮𝘶𝘯𝘪𝘵𝘺, 𝘢𝘯𝘥 𝘦𝘯𝘩𝘢𝘯𝘤𝘦 𝘴𝘬𝘪𝘯 𝘨𝘭𝘰𝘸.

𝘕𝘰𝘸 𝘢𝘷𝘢𝘪𝘭𝘢𝘣𝘭𝘦 𝘱𝘦𝘳 𝘴𝘦𝘴𝘴𝘪𝘰𝘯.
𝘓𝘪𝘮𝘪𝘵𝘦𝘥 𝘴𝘭𝘰𝘵𝘴 𝘥𝘢𝘪𝘭𝘺.

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Your body makes collagen constantly. But the version it assembles first isn't finished. Before collagen can hold its shape, an enzyme has to modify specific amino acids in the chain. That enzyme needs vitamin C to work.

Here's what vitamin C actually does: it enables the chemical modification (hydroxylation) that allows three collagen chains to lock together into a stable triple helix. Without that modification, the collagen structure is so weak it falls apart below body temperature. Literally. Unhydroxylated collagen melts at about 24°C. Your body runs at 37°C. The only thing keeping your collagen intact at body temperature is the modification that vitamin C makes possible.

This is why scurvy causes bleeding gums, loose teeth, poor wound healing, and joint pain. Your body is still making collagen. It just can't hold together.

Vitamin C isn't recycled in this process. It's consumed each time. Your supply has to be continuously replenished.

Most collagen supplement studies co-administer vitamin C. The ones that don't rarely account for baseline vitamin C status. If you're taking collagen without adequate C, you're supplying the raw material without the tool that finishes it.

Sources: Peterkofsky, Am J Clin Nutr, 1991. Shoulders & Raines, Annu Rev Biochem, 2009.