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Cleveland Botanical Destination specializes in high quality CBD products from best USA brands.

07/27/2022

Today we will focus on the risk posed by cannabis or CBD interacting with medications that you may be taking. The risk from these interactions stems from either THC or CBD causing the level of the conventional medication to go either up or down. Generally, conventional medications are safe and effective within a range of blood levels. If the level gets too high, it can be toxic. If the level gets too low, the medicine can cease to work, which can be very dangerous too.
There is a column for CBD and a column for THC (cannabis). You’ll note that there are three designations in the columns (Y = there is an interaction, beware! N = no or no significant interaction. T = theoretical interaction but not seen or not concerning in the real world.)

As you can see, most of the meds that you asked about are relatively unaffected by either CBD or THC. The group of medications that I added are more concerning and are affected mostly by CBD. Of course, these are not complete lists and you should be aware that many medication-checker websites and applications are not complete or accurate when it comes to cannabis or CBD. The above lists cannot be considered medical advice and you should consult with MD.

05/24/2022

Cannabis is still SO misunderstood out in the world.

Despite the rising support for legalization, most people still think that people who consume cannabis are just “getting high” as a “recreational” activity.

But besides being an incorrect view of cannabis consumers, it’s also dead wrong. Here are some unexpected ways people use cannabis to improve their lives.

1. Cannabis to manage pain.

The right mix of cannabinoids, at the right dose, using the right delivery method, can be an EXTREMELY effective option for managing pain.

2. Cannabis to help you sleep.

A tiny dose of THC right before bed can often help you get the best night’s sleep of your life. I can’t tell you how many people were totally against cannabis, but told me they don’t sleep, tried a very small gummy at night, and now use cannabis daily (and have never felt better).

3. Cannabis to help you work out.

Let’s face it, one of the BIG problems around staying active is cultivating the motivation to actually go do it. Try a very tiny dose of cannabis right before it’s time to get moving, and you will be surprised how much more fun, enjoyable, and powerful you feel during your workout (or even just walking / hiking). This is my secret weapon for staying in great shape, no matter how busy I get.

4. Cannabis to improve your s*x life.

S*x is a complicated issue, and one that most couples struggle with. Try introducing a little cannabis, and you will both get in the mood faster, feel more pleasure, and WANT to have a lot more s*x! 😍

Photos from cbdhingetown's post 04/28/2022

As they say, different strokes for different folks. We said it before and will say it again, this is all personalized medicine.

03/29/2022

The endocannabinoidsystem is our favorite topic.

But let's be clear, our understanding of the system is JUST begining and frankly, the science we have done on the ECS is actually pretty flawed.

Science first framed this entire ECS concept around the idea that was the "master key" to the system...but instead it was a very specific key that only cannabis produces...

The truth is that our ECS is a huge, complex, and diverse system that uses the in your body and your diet to maintain

it is made up of MANY receptors and MANY signals...and THC and CBD interact more intricately than we every realized with these other receptors (GPR's) and ion channels (TRP's).

This larger system has been dubbed the - the magical system inside all of us!

Photos from cbdhingetown's post 03/18/2022

Sow Eden - IMMUNITY tincture stars CBDA (Cannabidiolic Acid) and CBGA (Cannabigerolic Acid), two extremely powerful raw and non-decarboxylated cannabinoids with very high bioavailability in the human body. Our new IMMUNITY formula combines these two cannabinoids in a 1:1(1500 mg CBDA and CBGA) + Ginger Root and Lemon Peel Extract for extra immune support.
CBDA’s activation of the 5-HT1A Serotonin receptor can confer an anxiolytic (anti-anxiety), antidepressant, and antipsychotic effect? The fact that the cannabis plant biosynthesizes CBDA is incredible!

01/13/2022

Compounds in cannabis can prevent infection from the virus that causes Covid-19 by blocking its entry into cells, according to a study published this week by researchers affiliated with Oregon State University. A report on the research, “Cannabinoids Block Cellular Entry of SARS-CoV-2 and the Emerging Variants,” was published online on Monday by the Journal of Natural Products.

The researchers found that two cannabinoid acids commonly found in h**p varietals of cannabis, cannabigerolic acid, or CBGA, and cannabidiolic acid, also known as CBDA, can bind to the spike protein of SARS-CoV-2, the virus that causes Covid-19. By binding to the spike protein, the compounds can prevent the virus from entering cells and causing infection, potentially offering new avenues to prevent and treat the disease.

As a complement to vaccines, small-molecule therapeutic agents are needed to treat or prevent infections by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and its variants, which cause COVID-19. Affinity selection-mass spectrometry was used for the discovery of botanical ligands to the SARS-CoV-2 spike protein. Cannabinoid acids from h**p (Cannabis sativa) were found to be allosteric as well as orthosteric ligands with micromolar affinity for the spike protein. In follow-up virus neutralization assays, cannabigerolic acid and cannabidiolic acid prevented infection of human epithelial cells by a pseudovirus expressing the SARS-CoV-2 spike protein and prevented entry of live SARS-CoV-2 into cells. Importantly, cannabigerolic acid and cannabidiolic acid were equally effective against the SARS-CoV-2 alpha variant B.1.1.7 and the beta variant B.1.351. Orally bioavailable and with a long history of safe human use, these cannabinoids, isolated or in h**p extracts, have the potential to prevent as well as treat infection by SARS-CoV-2.

01/12/2022

Real fruit gummies, nano-infused with Delta-9-THC, other cannabinoids, & strain-specific terpenes.

Durban Zkittlez - Taste like... Tutti frutti. Sativa dominant cross of Zkittlez (Grape Ape X Grapefruit) and Durban Poison, an indigenous sativa from the South African port city of Durban. Major terpenes... Limonene, a-Pinene, Valencene

Watermelon Sorbet - Taste like... Juicy watermelon. A new age cross of Gelato #45 (Sunset Sherbet X Thin Mint Girl Scout Cookies), Zkittlez (Grape Ape X Grapefruit), and Watermelon OG. Major terpenes... b-Caryophyllene, Limonene, Humulene

Sour Strawberry Cookies - Taste like... Strawberry jam, with a little sour kick. A balanced cross of Sour Diesel (Chemdawg X Super Skunk), Strawberry Haze (a highly regarded haze phenotype), and Animal Cookies (Fire OG X Girl Scout Cookies). Major terpenes... Terpinolene, a-Pinene, Myrcene

Granddaddy Sour OG - Taste like... Fruit punch with a bit of sour & grape. A heavy-hitting blend of iconic strains... Granddaddy Purple (Mendo Purps X Skunk X Afghan Kush), Sour Diesel (Chemdawg X Super Skunk), and OG Kush (Chemdawg X Lemon Thai X Hindu Kush). Major terpenes... Myrcene, b-Caryophyllene, Linalool

Vegan · Non-GMO · Gluten-Free

Photos from cbdhingetown's post 10/20/2021

We sourced a new product at a $25 price point per cart. This will replace what has been a great selling $30
item. When we roll out a product at a lower price, we want to assure you that quality isn’t sacrificed. PureKana is a big industry name with a great reputation. Just for those who want to dork out or know what we do our homework, we have included a full panel COA (certificate of analysis).

10/11/2021

Photos from cbdhingetown's post 10/05/2021

NEW VENDOR SPOTLIGHT

SOW EDEN was founded by Jacob and Lindsey, two LA love birds whose products are all made in-house, in small batches, with organic and ultra-premium ingredients that are honestly sourced.

GLOW - Citrus Bergamia, otherwise known as Bergamot, is an Italian variety of bitter orange renowned for its skin rejuvenating and mood-lifting qualities. Bergamot essential oil helps to alleviate inflammation from eczema, psoriasis, dry or flakey skin, rashes, as well as pain relief. Grapefruit’s antioxidant properties help shield and repair the skin from damaging UV rays and environmental toxins. This invigorating blend of citrus melds perfectly with the amazing properties of CBD. The total terpene content is over 3% in GLOW. Terpenes help deliver CBD through the skin.

BLOOM - We cannot speak highly enough about the aromatherapeutic benefits of true Rose essential oil. The intoxicating scent of the Damask Rose promotes emotional balance and wellness and calms the mind, body, and spirit. Researchers believe rose oil may stimulate the brain to release endorphins, the “feel-good” hormone, as well as dopamine. A number of clinical studies have found that rose oil helps to improve the symptoms of depression, while another study found that when rose oil was applied topically, blood pressure, heart rates, breathing rates, and cortisol levels all decreased. The subjects also reported feeling much more relaxed following the treatment. The combination of true rose essential oil and broad-spectrum CBD provides powerful relief from inflammation and discomfort, especially pain associated with the menstrual cycle such as abdominal cramping and lower back pain.

CALM - One of Calm's powerhouse ingredients, cinnamon bark oil, encourages blood circulation and helps to alleviate pain and inflammation. Cinnamon also possesses anti-aging qualities by increasing collagen expression on the skin through its main chemical component, Cinnamaldehyde. The other main ingredient, vanilla bean, has anti-inflammatory benefits as well, so Calm helps to soothe irritated skin and is rich in the bioflavonoid/antioxidant, Vanillin, which helps protect against…

10/01/2021

New Vendor Spotlight - Gron! Pronounced grew-n, meaning green in Swedish.The CALM products are your daily dose of natural Zen, designed to promote relaxation and calmness. The calm CBD blend is infused with broad spectrum h**p and adaptogens such as GABA, Calcium and L-Theanine, Lavender and Chamomile. SNOOZE is your ticket to dreamland. Formulated to promote better, deeper sleep with broad-spectrum CBD + CBN, and adaptogens such as valerian root, lavender, and tart cherry.

Photos from cbdhingetown's post 09/29/2021

Lions Mane (Brain) - this Hedgehog Mushroom has a long history of usage in traditional Chinese medicine. This mushroom is rich in some physiologically important components, especially B-glucan polysaccharides, which may be responsible for antioxidant and neuro-protective activities which may improve memory, focus and dreaming.
Cordyceps(s*xual organs and lings) - Traditional healers in Sikkim recommend the fungus/mushroom Cordyceps militaris as a tonic, as they believe it improves energy, appetite, stamina, libido and endurance.
Reishi( liver and heart) - In the supplement to Classic of Materia Medica and the Ben Cao Gang Mu, which is considered the first pharmacopoeia in a China, the Reishi mushroom was attributed with possible therapeutic properties such as tonifying effects, enhancing vital energy, strengthening cardiac function, increasing memory and anti aging effects.
Kakadu Plum - is considered a gift of the Dreamtime and has been an important bush food for millennia to Indigenous communities in Northern Australia, used to treat skin conditions and sores or drunk as a tea to treat colds and flu. The fruit contains the highest recorded level globally of natural vitamin C content and displays superior antioxidant properties.

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2823 Detroit Avenue
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